Analysis of Dicamba and 2,4-D by Shimadzu’s Triple Quad LCMS-8060

Shimadzu’s app note demonstrates the sensitivity of the LCMS-8060 when analyzing dicamba and 2,4-D in a solution of 100x diluted glufosinate herbicide that contains a high amount of surfactants and other potential mass spec interferants.

The LC/MS/MS method was quickly developed with readily available mobile phases. Dicamba in methanol 0.01 and 0.025 ppb had a S/N of 3/1 and 10/1, respectively. 2,4-D in methanol at 0.0001 and 0.001 ppb had a S/N of 13/1 and 90/1, respectively.


Visit Shimadzu Pittcon 2018 in Orlando

Join Shimadzu at Pittcon 2018, where they will be showcasing their full range of instruments for the analytical community.

Be sure to visit booth 2734 to learn how Shimadzu can address your application requirements with their extensive portfolio of innovative, proven products.

Learn about new Shimadzu platforms and solutions:

  • Gas Chromatography
  • Microflow LC-MS/MS
  • FTIR Spectroscopy
  • MALDI-TOF Mass Spectrometry
  • Thermal Desorption GCMS


Get Fab results with Shimadzu’s proprietary, innovative nSMOL technique

nSMOL (nano-surface and molecular orientation limited proteolysis) is Shimadzu’s proprietary, innovative technique that enables selective proteolysis of the Fab region of monoclonal antibodies.

The nSMOL Antibody BA Kit is a ready-to-use reagent kit for collecting monoclonal antibodies from blood or other biological samples using immunoglobulin collection resin, and then performing selective proteolysis of the Fab region of these antibodies via trypsin-immobilized nanoparticles.