Analysis of Dicamba and 2,4-D by Shimadzu’s Triple Quad LCMS-8060

Shimadzu’s app note demonstrates the sensitivity of the LCMS-8060 when analyzing dicamba and 2,4-D in a solution of 100x diluted glufosinate herbicide that contains a high amount of surfactants and other potential mass spec interferants.

The LC/MS/MS method was quickly developed with readily available mobile phases. Dicamba in methanol 0.01 and 0.025 ppb had a S/N of 3/1 and 10/1, respectively. 2,4-D in methanol at 0.0001 and 0.001 ppb had a S/N of 13/1 and 90/1, respectively.


Introducing new Restek Force performance LC columns: dependable, scalable, exceptional quality

Restek’s Force LC columns give you the power to maximize instrument uptime, increase productivity, and transfer methods across your entire lab, from your trusted-but-aged HPLC to the cutting-edge UHPLC you just plumbed last week. This incredibly rugged and supremely consistent column line represents the culmination of Restek’s twenty-plus years in LC dedicated to continually improving their phase chemistries, their lot and lifetime testing, and their bonding and packing procedures.

  • Long-lasting and reproducible—maintain stable retention times and peak shapes, even under the stress of elevated UHPLC pressures and rapid cycling.
  • Fully scalable between 3 or 5µm HPLC and 1.8µm UHPLC—easily transfer and optimize methods without extensive calculations.
  • Premium quality ensured by strict manufacturing and QC procedures—Force LC columns are backed by the strength of Restek’s 100% Pure Satisfaction guarantee.

Meet today’s workflow needs—and prepare for tomorrow’s—by applying Force LC columns to all of your instrument platforms.

Purchase Restek Force LC Columns


LC-MS/MS Method for Evaluation of PPCPs in Environmental Water

Pharmaceutical and personal care products (PPCPs) encompass a family of compounds used by individuals for health and cosmetic purposes, as well as compounds used by the agricultural industry to maintain health of livestock. These contaminates are introduced into local waterways via sewage plants and natural disposal.

Check out Mandel’s selection of Shimadzu LC-MS/MS here.