Shimadzu’s app note demonstrates the sensitivity of the LCMS-8060 when analyzing dicamba and 2,4-D in a solution of 100x diluted glufosinate herbicide that contains a high amount of surfactants and other potential mass spec interferants.
The LC/MS/MS method was quickly developed with readily available mobile phases. Dicamba in methanol 0.01 and 0.025 ppb had a S/N of 3/1 and 10/1, respectively. 2,4-D in methanol at 0.0001 and 0.001 ppb had a S/N of 13/1 and 90/1, respectively.
Antibiotics present in food pose a serious public health issue. Allergies to sulfonamides are very common, and the increasing popularity of antibiotics is driving microbial resistance against current antibiotics.
Monitoring the Maximum Residue Levels (MRLs) has proven essential for public health, with the MRLs for some compounds set to low ppb levels. HPLC-MS/MS is very effective at analyzing trace-level antibiotics because it is selective, fast, and very sensitive for all the compounds of interest.
Mandel offers a wide range of Shimadzu LC equpiment. You can get a look at them here.
Read Shimadzu’s application note.
EDX and FTIR are widely used for analysis of foreign contaminant matter, but recently, these instruments are increasingly being utilized in tandem to conduct contaminant analysis.
While identification using any of these instruments and analytical methods independently is limited to some degree, using them in conjunction with one another permits a more detailed elucidation of the contaminant characteristics, thereby enhancing the validity of the respective results.