Steroid Detection in Small Volume Blood by LC-MS/MS

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) has become a successful immunoassay substitute for steroid detection in clinical research laboratories.

Shimadzu has composed an application note that describes a customized LC-MS/MS method which demonstrates a significant correlation between steroid concentrations in fingerstick versus vein blood. The sensitivity level for steroid detection demonstrated by this LC-MS/MS assay allows for a potential substitute to the classical immunochemistry assay.

Check out Shimadzu’s application note here.